Yes! You can utilize the rule trigger "If a task falls during a holiday or time off..."

This trigger allows you to take action when a task gets scheduled during a holiday or a user's scheduled time off.

The detail about this trigger and how to use it can be found here.

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We know that some people would also like to be able to tell Flowsana to skip over holidays/time off on Dynamic Duration and Auto-Adjust workflows, and we are considering adding this capability as a product enhancement in the future. You can upvote this enhancement request on our Feedback Portal.